Plasma Renin Activity Enzyme-Kinetic Assay: Protection of Angiotensin I from Bacterial Degradation
نویسندگان
چکیده
an indexing spot in the microarray is an effective approach to alert for heterophilic antibody interference in antibody microarray–based immunoassays; however, results obtained with the unrelated monoclonal antibodies of the index spot may not be totally the same as the capture antibodies in an antibody array. As more samples are tested, samples with confusing results that cannot be interpreted with the MMAB index may also be found. Thus, there remains a need to improve and explore identification methods for such samples.
منابع مشابه
Plasma renin activity enzyme-kinetic assay: protection of Angiotensin I from bacterial degradation.
Bystrom et al. (1 ) recently reported substantial peptidase activity in human plasma that had been incubated at 37 °C to generate angiotensin I (Ang I) during the clinical plasma renin activity (PRA) assay. If this result is correct, it would call into question many of the PRA results previously reported by our laboratory and by Quest Diagnostics, especially those with low PRA ( 0.65 g L h ). W...
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